Education
B.Sc., Biochemistry - FCUL, University of Lisbon
M.Sc., Medical Biochemistry - FCUL, University of Lisbon, Bruno Silva-Santos Lab
Ph.D., Infection Biology - Hannover Biomedical Research School, Immo Prinz Lab

Memberships
German Society of Immunology, Member
American Association of Immunologists, Member

Publications

Riemann L., Gutierrez R., Odak I., Barros-Martins J., et al., Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traits, under revision in EBioMedicine

Odak I, Riemann L, Sandrock I, Cossmann A, Ramos GM, Hammerschmidt SI, Ritter C, Friedrichsen M, Hassan A, Dopfer-Jablonka A, Stankov MV, Weskamm LM, Addo MM, Ravens I, Willenzon S, Schimrock A, Ristenpart J, Janssen A, Barros-Martins J, et al., Systems biology analysis reveals distinct molecular signatures associated with immune responsiveness to the BNT162b COVID-19 vaccine. EBioMedicine. (2024) doi: 10.1016/j.ebiom.2023.104947.

Yang T., Barros-Martins J., et al, RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery, Cell Rep. (2023) doi: 10.1016/j.celrep.2023.113230

Barros-Martins J., et al, Omicron infection-associated T- and B-cell immunity in antigen-naive and triple-COVID-19-vaccinated individuals, Front Immunol. (2023) doi: 10.3389/fimmu.2023.1166589

Behrens G.M.N., Barros-Martins J., et al, BNT162b2 boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19, Nat Commun. (2022) doi: 10.1038/s41467-022-32527-2.

Barros-Martins J., et al, OMIP-084: 28-color full spectrum flow cytometry panel for the comprehensive analysis of human γδ T cells, Cytometry Part A (2022) doi:10.1002/cyto.a.24564.

Barros-Martins J., et al, NK cell dysfunc􀆟on in severe COVID-19: TGF-β-induced downregulation of integrin beta-2 restricts NK cell cytotoxicity, Signal Transduction and Targeted Therapy (2022) doi:10.1038/s41392-022-00892-5

Bošnjak B., Odak I., Barros-Martins J., et al, Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents, Frontiers in Immunology (2021) doi:10.3389/fimmu.2021.772240

Barros-Martins J., et al, Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination, Nature Medicine (2021). doi:10.1038/s41591-021-01449-9

Schultze-Florey CR, Kuhlmann L, Raha S, Barros-Martins J, et al., Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI. Blood Adv. (2021) doi: 10.1182/bloodadvances.2020004073.

Ullrich L, Lueder Y, Juergens AL, Wilharm A, Barros-Martins J, et al., IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer's Patches of Mice. Front Immunol. (2021) doi: 10.3389/fimmu.2021.729607.

Cossarizza A, Chang HD, Radbruch A, Abrignani S, Addo R, Akdis M, Andrä I, Andreata F, Annunziato F, Arranz E, Bacher P, Bari S, Barnaba V, Barros-Martins J. ,et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). Eur J Immunol. (2021) doi: 10.1002/eji.202170126.

Odak I., Barros-Martins J., et al, Reappearance of effector T cells is associated with recovery from COVID-19, EBioMedicine (2020) doi: 10.1016/j.ebiom.2020.102885

Tan L, Sandrock I, Odak I, Aizenbud Y, Wilharm A, Barros-Martins J, et al., Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells. Cell Rep. (2019) doi: 10.1016/j.celrep.2019.05.064.

Wilharm A, Tabib Y, Nassar M, Reinhardt A, Mizraji G, Sandrock I, Heyman O, Barros-Martins J, et al., Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis. Proc Natl Acad Sci (2019) doi: 10.1073/pnas.1818812116.

Cossarizza A,..., Barros-Martins J., et al., Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). Eur J Immunol. (2019) doi: 10.1002/eji.201970107.

Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, et al., Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells. J Exp Med. (2018) doi: 10.1084/jem.20181439.

Lino C.N.R., Barros-Martins J., et al, Eomes expression reports the progressive differentation of IFN-γ-producing Th1-like γδ T cells. Eur J Immunol (2017) doi: 10.1002/eji.201646753.

Camelo C, Vilas-Boas F, Cepeda AP, Real C, Barros-Martins J, et al., Opi1p translocation to the nucleus is regulated by hydrogen peroxide in Saccharomyces cerevisiae. Yeast (2017) doi: 10.1002/yea.3240.

Barros-Martins J., et al, Effector γδ T Cell Differentation Relies on Master but Not Auxiliary Th Cell Transcription Factors, J Immunol. (2016) doi:10.4049/