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Edelblum Lab

 IBD research laboratory at Mount Sinai School of Medicine studying immune/epithelial interactions to better understand the underlying causes of Crohn's disease and discover potential new areas for therapeutic development

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3.1 million Americans

LIVE WITH INFLAMMATORY BOWEL DISEASE

Crohn's disease and ulcerative colitis affect 1.3% of the population with 70,000 new cases diagnosed every year. IBD is caused by a combination of genetic and environmental factors that lead to an abnormal immune reaction to the normal bacteria found in the intestine.

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Our latest publication in Science Immunology  shows that multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis. Congrats to Weili and Natasha (with an assist from Irving) on their hard work!

March 21, 2025

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Sara gave a stellar defense and capped off an amazing run of Rutgers Ph.D. students in the lab!

March 18, 2025

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Ananya's acceptance to ISMMS PhD Program

Everyone in the lab is elated that Ananya will be staying on after she completes her Master's this spring as a newly accepted IMM MTA Ph.D. student at Mount Sinai. Congrats Ananya!

March 2025

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We're ready to rally and be part of the large movement to ensure that biomedical research continues to thrive in the United States. Come join us in Washington Square Park and show your support of NIH, CDC, NSF and the other government agencies that fund the basic science research that is fundamental to human health!

March 7, 2025

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We're excited to welcome our Ben Pundyk (clinical coordinator) and Joana Barros Martins to Mount Sinai!

March 2025

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Sayra joins the Translational Immunology T32

As the newest appointee on Mount Sinai's Translational Immunology T32, we look forward to great things as Sayra works to understand the contribution of purinergic signaling on gamma delta IELs.

February 2025

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Copyright 2017 Karen Edelblum

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